The main reason to change your oil is to clean your engine. The oil contains fine wear particles that the filter doesn't pick up. Changing the oil gets rid of these particles, sludge and other harmful engine contaminates. The integrety of the oil outlasts its cleanliness. I change the oil when it starts to get black. This has been happening from 3-4k miles.
I use full synthetic because it reduces the time to get full oil pressure on start up. That's where most of the engine wear occurs. This is especially critical in colder climates.
Stock Ford Expedition oil (5W-20) is a synthetic blend.
Make sure your oil filter has the silicone valve that prevents drain back. Motorcraft oil filters have this. Walmart sells them and they are cheap.
That's my 2 cents.