The ones who say "it can't.....", or "it won't.......", need to sit back, zip lips, and let those who can and will, do it.
It will fit, bolt up to the existing trans. Will need mounts, possibly. Probably going to need a standalone and trans controller. How that will integrate to the body harness I don't know, but I'm sure it's not insurmountable, just $. I too am interested in this. I'm actually pretty intrigued and if I had the funds for the crate motor, it'd be happening. There's also a feller here wanting to put a 6.2 in his Expy. The electronics again are going to be the big obstacle to get past.
The mechanical stuff is out there. 6.2 were in 1/2T trucks, so there's mounts and the like available. The 7.3 might be different, then again, the mount bosses on the block might be the same as the 5.4, I'm not sure. I haven't found any info that confirms/disproves this. Of course mounts aren't nearly a thing if you know of a fab shop or race car builder. They could likely whip some up in short order assuming they add access to measurements and whatnot..