I have an 05, 5.4 4X4. I bought it used in Dec 2009. I get just over 14.306 around town, actually rural driving, and I'm averaging 16.943 for highway driving. In fact, on a recent trip to and from Colorado Springs from Indianapolis, I got exactly that. My overall average mileage for both around home and highway is 15.567. I keep a detailed record (Excel work sheet) on all my vehicles (9), as a check on performance and maintenance needs.
I usually fill up the Expedition around the 18-19 gallon point, but have gone as far as the 21 gallon point. Obviously, the longer I wait, there is a slight increase in overall mileage, as the weight of the vehicle is steadly decreasing.
I was hoping to get in the 20's when I bought it, but then opted for the 4X4 version. However, compared to my F-250 crew 4X4 that has averaged 12.213 over it's life so far, it's a big inprovement. But I also have two Escapes (08 auto I-4 4X2 and 05 4X4 manual I-4, and they average around 25 plus) that my wife and I drive daily.