This has become a huge issue. Prior to our current Expedition we purchased a CPO Mercedes GL 450 - what a POS. It was at the dealer all the time for repairs, MAJOR repairs no less. As soon as the warranty expired, we sold it and went back to an Expedition. Not that they are without there problems, but for the initial cost, the maintenance and upkeep has been reasonable in my opinion. It's not just cars though. We purchased a Dyson vacuum cleaner believing that it would last forever, two years later I had to find a vacuum repair shop (which surprisingly still exists) and the owner said if it wasn't for Dyson making such expense and crappy vacuums, their shop would have gone out of business long ago.
So what do you do, buy expensive and hope it's built with quality and lasts, or buy cheap and buy often. That used to be an easy question to answer.
Lastly, the other issue that drives me nuts is customer service. Once a dealer sells a car, the manufacturer and dealer seem like they couldn't care less about you. Again, not just cars though. Anyone have to call Comcast lately, might as well explain your cable problem to the wall.
I know these examples are anecdotal, but there is my rant too!