"This is my first body-on-frame vehicle so maybe my expectations are out of line but I feel a decent amount of up-and-down higher-frequency vibrations on a smooth road. It sort of feels like a tire out of balance but it doesn't seem to get better or worse with speed. Is this normal?"
This!!!! I have the exact same experience. I'm pretty sure it isn't the wheels. The vehicle I test drove did the same thing (Limited 302a package). I figured that vehicle had a bad wheel or something so didn't really worry about it. However, when I drove home my new vehicle (Limited 302A), I noticed the exact same thing! I only have 100 miles or so on it, but I hope I don't have to take it back to the shop.
I had a Toyota Sequoia (body-on-frame) before and there was nothing like this feeling.
Is CCD something you can turn off? If so, I'll see if that changes the ride.
Thanks, Dan