You know, that last part is a really good point. I hear tons of people saying "I hardly use 4 wheel drive, I don't need to change that front diff fluid". But what most people don't know is that on the Gen 1 trucks, the driver's side axle shaft turns all the time, and in doing so it turns the spider gears in the open diff. It doesn't turn the driveshaft, because the passenger side axle shaft gets disconnected in 2wd.
The bottom line is that the front diff fluid gets mucked up whether you use 4wd or not, so it needs regular attention.
Later trucks have IWE (integrated wheel ends) and may not have the same issues, but I'm not really that familiar with that setup.