I just did some googling and came across a similar issue and they resolved it with a relay PN It is the fuse relay. At Ford Dealership, the item is listed part # F5TZ*14N089*B RELAY LIST PRICE $16.24.
Here is their reply
"This relay has been replaced twice in our 2003 Ford Expedition. We were on the interstate when our vehicle shut down completely and had hard time maneuvering it. Vehicle would turn on and off. Always keep one in stock in vehicle. "
I am thinking it could be a possibility, as was said it happens when I have all the loads on like headlights, fogs, radio, front and rear AC and also it is very hot outside
It could be a possibiliyty that the relay is heating up, then stoping fuel flow and then it cools down and become operable??? The only thing that stops it seems is fuel flow, once the truck dies all the fans are still blowing strong etc so its only affecting fuel flow