I would only use tires that Michelin approves for your truck, for the 22” it is the Premier LTX only.
I have owned 1998, 2008 and now 2018 Expeditions. The ‘98 I had Michelin LTX as replacement tires and they were outstanding.
On the 2008 which had OEM Pirelli Scorpion All Season, tread wear was only fair and had a few punctures. On my 4 X 4 the front tires tended to wear on edges. The Scorpions were very smooth, quiet and towed well. I replaced with Michelin LTX and had lost about 2 mpg. I had Discount Tire replace with Continental Cross Track. The Continental’s performed ok, tread life was similar to Pirelli’s (just ok) but towing was not near as good as the OEM. Gas mileage was on par with the OEM tire.
On my 2018, I replaced Hankooks with Pirelli Verde All Season Plus II. These tires have been my favorite of all. They have much better wet traction than the Hankook’s, they tow well, they are quiet, get equivalent mpg’s as the OEM tire and the steering response is noticeably better. At 14k miles on these tires they seem to be wearing well and remain performing like new.
My two other vehicles have Michelin Tires. I love Michelin’s, however for my 22” rim Expedition I am forever sold on Pirelli.