That can be anything from a bad coil, sparkplug, clogged injector, exaust leak on that cylinder. Usual course is change spark plug for that cylinder, move coil to adjacent cylinder, see if code moves to that cylinder, if it does, replace that coil. if neither thing makes a difference, test plug going to that cylinders injector for power/pulse, if good replace that injector. Beyond that it gets fun, misfires are either easy, or a real SOB to narrow down. Try the first ones, with your ignition, and go from there. That misfire can be part of the shuddering your experiencing. An Automatic transmission is reliant on a smooth proper running engine to perform properly. We need to get your misfire fixed before you have anything else done to the trans itself.
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