1,000% the tire determines the ride. I paid for quality 305/45/22 tires and the ride is fantastic. Better than the OEM Pirelli Scorpions - maybe a little more noise at turnpike speed but the ride confidence and agility is double. I went from OEM 20" to Saleen 21", to aftermarket 20" in OEM size, to current F150 22" and can tell you the tires make the difference. When I had the 21's the tire selection was very limited. I bought General tires and was immediately disappointed. Took them completely off the truck with just a few thousand miles of use. Balance was dead on, experimented with PSI settings, eventually realized I bought something this side of Cooper.
A coworker put complete garbage 18 inch tires on his King Ranch Expedition and the ride is total crap. Nexen, a total 3rd rate brand. Every road expansion joint is amplified and the howling above 40 - 50 MPH is insane. And thats with the 65 aspect ratio sidewall that stubborn old men will tell you makes the difference in ride quality. You know, the ones who think all tread compounds are the same.
The $250K+ ultimate luxury SUV - Bentley Bentayga - has a variety of wheel/tire packages. All 20" or larger, 275 or 285 wide, 40 to 50 series, nothing taller. The rough riding rubber band tires, because Bentley owners enjoy a harsh ride.