My 2 cents re: ride that I've learned from (sometimes expensive) experience over the last 10 years or so:
** CONTEXT: I have lumbar disc injuries so softer ride is critical for me. I'm well past my stanced R34 pongo-stik suspension days.
-- Downsizing from 22" rubber-bands to tires with an actual sidewall dramatically softens up the ride as long as you don't do a stupid and put load range E tires on it.
-- The Max rides better than the normal length, by a significant margin.
-- The 2025 down-trim models ride noticeably worse even with the same 20" wheels as my 2020. (Loaners, man. If you can get 'em and use it as a test car to validate your experiences, it's valuable info.)
-- Tire pressure is a linear function from 0 PSI @ 0 load to max PSI/max load. Figure out how much your truck weighs (each axle) with the family in it and set them to that pressure. Yell if you need more details. I run my max at ~34-36 PSI cold. The difference between that and the 40+ on the door sticker is redonkulous. I wouldn't try this on 22's as big potholes or road debris can wreck your week with no sidewalls and lower tire pressures.
-- "Upgrading" the factory shocks to Bilstein has been an abject failure all three times I've tried it on Fords unless you love you some super-firm ride (see: stanced R34 comment above). Tried both 5100 and 4xxx (the yellow ones) and both rode like skateboards to me.
-- Any lift will make the ride harder unless you get offset or extended control arms to retain the factory (or longer e.g. Raptor) geometry.
-- Don't be so dead-set on factory wheels or some other fad wheel. Shop by load rating and weight, as the less weight on the wheel means less unsprung mass which means better control without sacrificing ride.
-- One reason I went with 265/70/18 Michelin Defender LTX M+S 116T SL for both the F-150 and the other Expedition is they have the load rating for very light towing while being a few pounds less than the OEM tires and significantly lighter than any Cooper or load range E tire. If you have to tow at GVWR capacity that limits options a bit but if the Michelins will work, I'd pick them. I haven't tried the M+S2 versions of those yet but I will in another year or two when my OEMs wear out.
-- Yes, Expeditions are based on a truck chassis but they should NOT ride like trucks unless you spec them like a truck, plan to tow heavy, and do some of the things mentioned above that make the "truck" ride worse. You can make a 1/2-ton truck ride like a 3/4-ton truck if you want but if you aren't going to use it like a 3/4-ton truck, why would you do it?
---- Addendum: you'll see people whining about how a 6000lb SUV doesn't handle well without hard shocks, 22" sport tires, and a super-thick anti-sway bar. So is this a sports car, a truck, or an SUV? Know your limitations.
Best of luck. Lots of good and bad info out there and it's hard to differentiate without spending a lot of money learning the hard lessons about Internet Wisdom(tm).