To the OP - I have the 22" rims and got 50K out of the stock Pirellis. Could have gone another 10K but winter was coming. Replaced those with Michelins and the ride got even better. I also have the CCD suspension. Had a "regular" Expy as a loaner and it rode like mine when I switch to comfort. A bit too spongy/wallowy for my taste. The 22's and suspension set to Normal is just right. And yes, I tow a 6500 lb trailer. All works great. I think you'll be fine looking for a better quality tire. The Michelins ride very quiet and soak up the expansion joints and normal road crap way better than the Pirellis.
If you are doing any light off-roading or live on a gravel road, then you have to make different decisions. Good luck!!
If you are doing any light off-roading or live on a gravel road, then you have to make different decisions. Good luck!!